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Elucidating Genetic and Epigenetic Mechanisms of Type 2 Diabetes Mellitus Pathogenesis

Barman, Nilima (© University of Dhaka, 2026-10-18)

Type 2 diabetes mellitus (T2DM) is a rapidly escalating public health crisis in Bangladesh, which now ranks seventh globally, with approximately 13.9 million adults living with the disease. T2DM is a multifactorial disorder ...
Molecular Basis of the Pelvi-Ureteric Junction Obstruction in Children with Hydronephrosis

SHADRUL ALAM, MOHAMMED (© University of Dhaka, 2025-11-05)

ABSTRACT: Background: Pelvi-Ureteric Junction Obstruction (PUJO) represents a significant cause of congenital hydronephrosis that can lead to progressive renal damage if untreated. While the condition is well-characterized ...
Impacts of pathogenic mutations and XmnI polymorphism on the severity of haemoglobin E β-thalassaemia patients in Bangladesh

Aziz, Md. Abdul (© University of Dhaka, 2025-07-07)

Background: Haemoglobin E β-thalassaemia is a common blood disorder in South Asia, especially Bangladesh. The disorder can range from mild and asymptomatic anemia to life-threatening anemia. Patients with asymptomatic ...
Expression and regulation of efflux transporters in chemoresistant breast, colon and ovarian cancer cells in Bangladeshi patients

Deb Nath, Sudipta (© University of Dhaka, 2025-04-20)

Chemotherapy is a cornerstone in cancer treatment, but multidrug resistance (MDR) poses a substantial challenge. Hyperactivity of efflux pumps is one of the vital reasons to confer MDR. P-GP, MRP1 and ABCG2- these key ...
Metabolomics Profiling for Amino Acidopathies of Infants in Hospital Based Settings in Bangladesh and Development of Easy-to-Use Kit for Disease Diagnosis and Monitoring

Hossain, Md. Shawkat (©University of Dhaka, 2025-02-09)

This study aimed to address the challenges associated with identifying inborn errors of metabolism (IEM) in resource-constrained environments, focusing on amino acid and galactose metabolism disorders in the Bangladeshi ...
Inborn errors of metabolism screening and profiling of amino acids, acylcarnitines and glucose-6-phosphate dehydrogenase deficiency in Bangladesh population

Sarker, Suprovath Kumar (University of Dhaka, 2021-08-29)

Similar to other lower and lower middle income countries, Bangladesh is facing the accelerated demographic shift from communicable diseases to non-communicable diseases (NCDs) including genetic disorders (GDs). Approximately ...
Genetic Spectrum and Metabolic Profiling of Congenital Hypothyroid Children in Hospital Care Settings in Bangladesh

Begum, Mst. Noorjahan (University of Dhaka, 2021-08-26)

Congenital Hypothyroidism (CH) is the deficiency of thyroid hormones at birth and a major cause of mental retardation if left untreated. The frequency of CH is much higher in Bangladesh than that of the global incidences ...
Genetic diversity among Bangali and seven ethnic groups of Bangladesh based on Y-chromosome

Hasan, Md. Mahamud (University of Dhaka, 2021-08-24)

A comprehensive population genetic study was conducted using 17 Y-chromosome specific microsatellites to decipher genetic diversity of the Bangladeshi populations from a Y-chromosome perspective. Seven ethnic populations ...
Detection of mutation and polymorphism in marker genes of cervical carcinoma in Bangladeshi patients

Zohura, Fatima Tuj (University of Dhaka, 2019-10-13)

Cervical cancer is a gynaecologic cancer type that develops in the cervix. Annually 528,000 new cases of cervical cancer are reported with 266,000 deaths, which account for 8% mortality of all female cancer patients. ...
Remedial Effects of Homeopathic Drugs against Chronic Suppuration of Ear Caused by Pathogenic Microorganisms

Hasan, Nazmul (2019-10-07)

Chronic Suppurative Otitis Media (CSOM) is known as one of the most common infectious disease and is characterized by a persistent discharge from the middle ear through a perforated tympanic membrane. CSOM is considered ...

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