Department of Biochemistry and Molecular Biology: Recent submissions

Now showing items 1-20 of 32

Association of Insulin Receptor and Peroxisome Proliferator-Activated Receptor γ Gene Polymorphisms with Phenotypic Features and Insulin Resistance in Women with Polycystic Ovary Syndrome

Nayeem, Jannatul (©University of Dhaka, 2024-04-30)

Introduction: Polycystic Ovary Syndrome (PCOS), the most prevalent endocrine disorder among reproductive-aged women, is characterized by three diagnostic phenotypic features: anovulation/ oligomenorrhea (AO/OM), polycystic ...
Mechanistic basis of low blood pressure and association of red cell distribution width with β-globin gene mutation patterns in Bangladeshi patients with E-β/β-thalassemia major

SULTANA, NUSRAT (©University of Dhaka, 2024-04-28)

Background Thalassemia has been recognized as a global public health problem. Bangladesh, with a carrier frequency of 11%, including 2% with β trait and 9% with E trait is negatively affected with this monogenic blood ...
Functional Characterization of Mitochondrial Small Heat Shock Protein Genes in Eggplant for Abiotic Stress Tolerance

Khatun, Mst. Muslima (©University of Dhaka, 2023-12-11)

Plants are sessile organisms and have evolved with numerous mechanisms for overcoming various environmental stresses. In response to various abiotic stresses, plants are used to transcribe a class of proteins known as ...
Genomewide analysis of Salmonella Typhi and Paratyphi A, B circulating in Bangladesh to understand the population structure, transmission pattern and evolutionary dynamics using whole genome sequencing

RAHMAN, SADIA ISFAT ARA (©University of Dhaka, 2023-11-22)

Enteric fever, caused by Salmonella enterica serovar Typhi (S. Typhi), Salmonella enterica Paratyphi serovars (S. Paratyphi A, B, and C), remains a major public health concern in low and middle income countries (LMIC) ...
Intestinal Permeability, Nutritional Status and MicroRNA Expression in Children Living in Slum Area of Bangladesh

Rashid, Humaira (©University of Dhaka, 2023-10-08)

Background: Intestinal barrier dysfunction is a global problem especially in poor settings like Bangladesh where malnutrition and recurrent pathogenic infections are very common. The intestinal epithelial barrier maintenance ...
Study of p53 gene polymorphism and risk of hepatocellular carcinoma: in a Bangladeshi cohort

Rahman, Md. Abdur (©University of Dhaka, 2023-09-07)

Hepatocellular carcinoma (HCC) is the number one malignancy of the liver, the 5th leading cancer death throughout the world. Most liver cancers are related to gene polymorphism, specifically the p53 tumor suppressor gene ...
Association of Type 2 Diabetes Related SNPs with Predisposition of Gestational Diabetes Mellitus in Bangladeshi Women

Amin, U.S. Mahzabin (©University of Dhaka, 2023-02-23)

Background: Recent advances in genetic studies have revealed a number of susceptible loci for Type 2 diabetes mellitus (T2DM). In this study, we attempted to analyze the independent effect of variants in some of these loci ...
Prevalence and Mutation Spectrum of Thalassemia Carriers and Study of Genetic Modifiers Affecting the Disease Severity of HbE/β-Thalassemia in Bangladeshi Population

Noor, Farjana Akther (©University of Dhaka, 2023-02-09)

Background: As being a country of the global thalassemia belt, β-thalassemia, a hereditary hemolytic disorder caused by reduced or absent synthesis of the β-globin chain of the hemoglobin tetramer (α2β2) is the most common ...
Impact of Introducing High-Selenium Lentils on Everyday Diet for Mitigating Arsenic Related Health Problems in Bangladesh

Akhtar, Evana (©University of Dhaka, 2022-04-13)

Background: Chronic arsenic (As) toxicity (arsenicosis) due to consumption of ground water polluted with higher level of As is a major global environmental problem. Worldwide, above 100 million people are found to be ...
Drought and salt tolerance characteristics of rice plants transformed with the SNAC1 transcription factor

Tammi, Rumana Sultana (©University of Dhaka, 2022-02-22)

Abiotic stresses are one of the major problems for restricting food production around the world. Plant survival and crop production has been hampered due to environmental stresses such as salinity and drought. Some plants ...
Association of TNF-α, IL6 and IL-10 gene Polymorphisms with Type 2 Diabetes Mellitus in Relation to Insulin Secretion and Action in Bangladeshi Population

YEASMIN, ROKSANA (©University of Dhaka, 2022-02-22)

Type-2 DM is a polygenic, metabolic illness. It is categorized by prolonged high blood glucose levels as well as unregulated blood pro-inflammatory cytokines by the influence of several genes. A research was conducted ...
Association of TNF-α, IL6 and IL-10 gene Polymorphisms with Type 2 Diabetes Mellitus in Relation to Insulin Secretion and Action in Bangladeshi Population

Yeasmin, Roksana (©University of Dhaka, 2022-01-16)

Type-2 DM is a polygenic, metabolic illness. It is categorized by prolonged high blood glucose levels as well as unregulated blood pro-inflammatory cytokines by the influence of several genes. A research was conducted ...
Assessing the effect of artificially reduced lignin content in jute with regard to its use as textile fiber, biofuel and raw material for paper-pulp industry

Nath, Mousumi (University of Dhaka, 2021-09-19)

Jute (Corchorus sp.), a lignocellulosic plant grown abundantly in Bangladesh, is known for its fiber quality. Agriculture-based, renewable and biodegradable nature together with low-cost availability puts jute at an ...
Guillain-Barré syndrome in Bangladesh: genetic polymorphism and pathogenesis

Hayat, Shoma (University of Dhaka, 2021-08-29)

Guillain-Barré syndrome (GBS) is a rapidly progressive, immune-mediated, paralytic disorder of the peripheral nervous system, which has led to significant morbidity and disability in the post-poliomyelitis era. Annually, ...
Association of NAT2, GSTT1 and GSTM1 gene polymorphism and influence of oxidative stress on prostate cancer risk in Bangladeshi population

Nesa, Ayatun (University of Dhaka, 2021-08-19)

Prostate cancer (PCa) is the second leading cause of cancer-related mortality in men. Prostate epithelial cell express phage II metabolizing enzymes, and recent molecular epidemiological studies have analyzed the ...
Association of Genetic Variation in TCF7L2, SLC22A1 and KCNJ11 Genes with Risk for Type 2 Diabetes in Bangladeshi Population

Vaumik, Amrita (University of Dhaka, 2021-08-19)

Type 2 diabetes mellitus (T2DM) is a multifactorial disease. Its prevalence has been rapidly increasing throughout the world, which is associated with several gene polymorphisms including KCNJ11, TCF7L2, SLC22A1 etc. The ...
Nutritional Assessment of Leukemic Children and its Relationship with serum Selenium, Zinc and Copper

Siddiqua, Khurshida Azad (University of Dhaka, 2020-11-04)

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer and accounts for 30 – 35% of all cancers in children. Only 50 years ago, the disease was uniformly fatal with an Overall Survival (OS) rate < 5%. In ...
Comparative study of biochemical parameters of cardiac patients from different regions of Bangladesh

Yasmin, Mrs. Sabina (University of Dhaka, 2020-10-18)

Globally, cardiovascular diseases are the number one cause of death and are projected to remain so. An estimated 17.5 million people died from cardiovascular disease in 2005, representing 30 % of all global deaths. Of ...
Characterization of a Bangladeshi rice landrace Horkuch as a suitable donor for salinity tolerance traits for development of new salt tolerant rice cultivars

Khan, Sumaiya Farah (University of Dhaka, 2019-01-23)

Bangladesh is a low-lying developing country adversely affected by climate change with its coastal area under constant threat of hazards like floods, cyclones, high temperature, sea level rise, salinity intrusion, etc. The ...
Identification, characterization and validation of the genes involved in salt tolerance of the rice (Oryza sativa L. indica) landrace Horkuch and its segregating population using RAD-genotyping and RNA-sequencing under salinity stress

Elias, Sabrina Moriom (University of Dhaka, 2018-07-29)

Plants being sessile organisms, possess excellent means of sensing and regulation to adjust with the environment and its change. Molecular exploration of indigenous landraces adapted to various stresses in such environments ...

Now showing items 1-20 of 32

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