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Now showing items 1-20 of 35

Genetic polymorphism of GSTM1, GSTP1 in lung cancer patients of Bangladesh

Nasir Uddin, Mir Muhammad (University of Dhaka, 2014-04-10)

Lung cancer has been the most common cancer in the world for several decades, and by 2008, there were an estimated 1.61 million new cases, representing 12.7% of all new cancers. It was also the most common cause of death ...
Biological and pharmacological screening of natural products isolated from tinospora crispa (L.) hook.f. and thoms and stephania japonica (Thunb.) miers. (Family-Menispermaceae)

Bokshi, Bishwajit (University of Dhaka, 2014-06-26)

Two medicinal plants of Bangladesh, Tinospora crispa (L.) Hook.f. & Thoms (Family Menispermaceae) & Stephania japonica (Thunb.) Miers (Family: Menispermaceae) has been investigated for the isolation of natural products & ...
Studies of some cytotoxic plant materials

Ali, Husne Ara (University of Dhaka, 2014-07-15)

Cancer is a deadly disease all over the world. Modern treatments of cancer include surgical resection, radiation therapy, chemotherapy and phytomedicine. A strong effort has been put into the search for novel anticancer ...
Effect of GSTP1 and ABCC4 gene polymorphisms on response and toxicity of cyclophosphamide-epirubicin-5-fluorouracil based chemotherapy in Bangladeshi breast cancer patients

Islam, Md. Siddiqul (University of Dhaka, 2014-10-27)

Chemotherapy is one of the most widely used treatments of breast cancer with the limitation of significant inter-individual heterogenecity in response as well as in toxicity. The most important cytotoxic drug namely ...
Bioactivity guided isolation of active principles from spondias pinnata of Bangladesh

Muhammad, Ashif (University of Dhaka, 2015-03-15)

One medicinal plant of Bangladesh, Spondias pinnata (Kurz) (Family: Anacardiaceae) has been investigated for the isolation of its secondary metabolites and evaluation of pharmacological activities. The powdered fruits and ...
The potentiation and broadening the effect of low molecular hypoglycemic drugs through interaction with some CNS stimulant molecules

Mohiuddin, Mohammad (University of Dhaka, 2015-03-18)

The in-vitro study on the interaction of caffeine and theophylline with gliclazide, glipizide, glyburide and metformin has been carried out by IR spectroscopy, UV spectrophotometric, continuous variation, mole ratio, ...
BRCA1, BRCA2, HER2 and RAD51 gene polymorphisms in breast cancer patients of Bangladesh

Parvin, Salma (University of Dhaka, 2015-06-11)

Purpose: Breast cancer is the most common malignancy among females in both developed and developing region of the world. Genetic factors are implicated in the etiology of breast cancer. Altered expression of some genes due ...
Pharmacokinetics of naproxen in Bangladeshi type II diabetic patients treated with gliclazide

Pal, Tushar Kanti (University of Dhaka, 2015-12-28)

This study was aimed to investigate pharmacokinetics of naproxen in Bangladeshi type II diabetic subjects treated with gliclazide. All the subjects were divided into three groups; group G, diabetic subjects only took ...
Cytotoxic and anti-microbial constituents from some Bangladeshi Bridelia and Erythrina species

Anjum, Adeeba (University of Dhaka, 2016-06-02)

This thesis describes the isolation and structure elucidation of secondary metabolites from four plants Bridelia verrucosa, B. stipularis, B. tomentosa (Family: Phyllanthaceae) and Erythrina fusca (Family: Fabaceae) as ...
Bioavilability enhancement of poorly water soluble drugs using Self Emulsifying Drug Delivery System (SEDDS) and Solid Dispersion (SD) technology

Islam, Sardar Mohammad Ashraful Islam (University of Dhaka, 2016-06-02)
Development and validation of chromatographic methods for the determination of drug substances, impurities and residual solvents by RP-HPIC/GC

Hossain, Md. Faisal (University of Dhaka, 2016-08-28)

The purpose of this study was to develop and validate chromatographic methods to characterize pharmaceutical drug substance/product in terms of potency/purity, impurities, solubility, stability, and ionization constant. ...
A Pre-clinical investigation on hepatotoxicity and osteoporosis induced by amphetamine derivative (methamphetamine and 3, 4-methylenedioximethamphetamine) with associated metabolic pathways using rat

Akhter, Nasrin (University of Dhaka, 2017-05-08)

Abuse of amphetamine derivative as methamphetamine (Meth, Yaba) or 3, 4-methylenedioximethamphetamine (MDMA, Ecstasy) is on a raising trend globally and Bangladesh is not an exception of this. The long term effects of ...
Effect of SULT1A1, UGT2B7, CYP3A5 and CYP2D6polymorphisms on tamoxifen response in breast cancer patients of Bangladesh

Al-Mamun, Mir Md. Abdullah (University of Dhaka, 2017-06-05)

Breast cancer is the leading cause of cancer death in females worldwide as well as in Bangladesh. Tamoxifen (TAM), selective estrogen receptor modulators (SERMs), is the most commonly used agent for the treatment of estrogen ...
Serum trace elements, antioxidant-vitamins, immunoglobulins, lipid peroxidation, cortisol, amino acid level in patients with major depressive disorder and their correlation with disease status

Islam, Md. Rabiul (University of Dhaka, 2017-06-07)

Background: Major Depressive Disorder (MDD) is a mental disorder characterized by a pervasive and persistent low mood which is accompanied by low self-esteem and loss of interest or pleasure in day to day activities that ...
Chemical and biological studies of some medicinal plants used by the small ethnic community people of Chittagong hill tracts

Ibrahim, Mohammed (University of Dhaka, 2019-03-28)

This dissertation describes the isolation and characterization of compounds from the leaves of Murraya koenigii (L.) Spreng (Fam.- Rutaceae) and Baliospermum montanum Willd. (Fam.- Euphorbiaceae) as well as the isolation ...
Pharmacological and biochemical investigations of methanolic extract of Myristica fragrans seeds

Bhuiyan, Md. Shaiful Alam (University of Dhaka, 2019-04-24)

The methanolic extract of Myristicafragransseeds and fractions of petroleum ether, n-hexane and chloroform screened for phytochemical analysis and revealed the presence of alkaloids, flavonoids, carbohydrates, glycosides, ...
Genetic polymorphisms of GSTP1,XRCC1, XPC and ERCC1: prediction of clinical outcome of platinum-based chemotherapy in advanced non-small cell lung cancer patients of Bangladesh

Bushra, Most. Umme (University of Dhaka, 2019-05-26)

Background: Lung cancer is the second leading cause of cancer related death worldwide as well as in Bangladesh. Platinum-based chemotherapy is considered as the first-line treatment for lung cancer. But non-small cell lung ...
Quality Assessment of Some Commonly Used Enantiomeric Drugs in Bangladesh

Rahman, Asma (University of Dhaka, 2019-10-03)

This thesis describes rapid, accurate, precise, less time consuming analytical methods with excellent resolution for separation and determination of chiral drugs. By performing significant number of trial and error methods ...
Degradation kinetic studies of non-pharmacopeial drug products and determination of their forced degradants and Impurities

Sultana, Sharifa (University of Dhaka, 2019-10-06)

Stability of a drug is assessed to ensure the chemical and physical integrity of the drug product and its capacity to remain protected against exposure to environment, such as air, light, and heat throughout its shelf-life. ...
Studies of stress degradation and impurity profiles of some 5-ht3 antagonists

Hossain, Md. Mokaram (University of Dhaka, 2019-10-06)

Three issues of fundamental importance in drug therapy are safety, efficacy and stability. This thesis paper has reports the scientific data of five 5-HT3 antagonists in the field of stress degradation, degradation ...

Now showing items 1-20 of 35

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